The Administration has made artificial intelligence (AI) a key technology priority area, notably through the launching of the American AI Initiative. In addition to establishing strategic areas of emphasis for U.S. AI research and development (R&D), the American AI Initiative directed Federal agencies to take specific actions that support its objectives. The Administration has called for record amounts of AI R&D investment, led the development of the first international statement on AI Principles, issued the first-ever strategy for engagement in AI technical standards, published the first-ever reporting of government-wide non-defense AI R&D spending, and released the first-ever AI regulatory document for the trustworthy development, testing, deployment, and adoption of AI technologies. Most recently, the Administration launched the first round of NSF-led AI Institutes to ensure continued U.S. leadership in AI R&D. This talk will discuss many of these key accomplishments of the Administration in AI, which are collectively advancing U.S. leadership in AI, improving quality of life, and strengthening U.S. economic competitiveness.